• Reduce text

    Reduce text
  • Restore text size

    Restore text size
  • Increase the text

    Increase the text
  • Print


An agro ecological approach, with high stakes in Animal and Public health

The STReP program follows an agro ecological approach in setting up new strategies for the control of livestock parasites and a lowering of the use of chemical treatments.  STReP answers major issues in Animal and Public Health.

Poules dans un pré © PierreJ (Flickr, Creative Commons)
Updated on 12/17/2013
Published on 11/26/2013

STReP (drastic and Sustainable Treatment Reduction against Parasitism in livestock) is carried out by Nathalie MANDONNET and Jacques CABARET. It is a part of the "scope" project within GISA’s international program of the AMI (Call for expression of interest)  2012 of the GISA “métaprogramme”.

Gastrointestinal nematodes and Coccidiodis: identical issues

At a global scale, parasitic diseases in livestock bear clinical signs and often lead to high mortality rates, marked by lower productions, by-products, lower manure and traction. Among parasitic diseases, gastrointestinal nematodes (GIN) in herbivores and coccidiosis in poultry are a major concern for breeders.
Over the last decades, the lack of efficiency of antiparasitic treatments led  breeders to change their parasite eradication methods to an upstream move of the host parasite balance towards the host, with various biotechnical methods  (supplement and enhancement of the use of antihelmintic (anti worm) plants, mixed grazing areas shared by animals of different  biological susceptibility responses.

Nématodes gastro-intestinaux et coccidies © STReP
Nématodes gastro-intestinaux et coccidies © STReP

This new method follows an agro ecological approach:

  • improve the implementation of animals and plants in the production system
  • restore diversity in the breeding systems
  • put the breeder back at core for decision making regarding his/her livestock health

Pâturage mixte © STReP
Pâturage mixte © STReP

STReP’s Objectives

STReP in the GISA program offers new strategies combining both a sustainable control of the GIN and coccidiosis, and a drastic lowering of chemical use:

  • experimental testing of various biotechnical tools within a global approach for herbivores and poultry.
  • a hierarchy of tools thanks to epidemiological and risks analysis modelling.
  • academic knowledge production on certain tools (genetic determinism of the host resistance,  antihelmintic  substances mechanisms...). This knowledge should reinforce the generic function of patterns)
  • knowledge transmission  through the associated veterinary schools.

host-response STReP. © INRA
host-response STReP © INRA

A 3 scale organization

The project relies on 6 Workpackage (WP) at 3 different levels: a biotechnical level, a systemic level, a society-territory level.  STReP tackles GISA’s first ambition: « Comprendre l’hôte et ses pathogènes » dans ses WP1 à WP4.
"understand the animal and its pathogens" with the Workpackages 1 and 4. Ambition 2 related to "building health in farming and systems" is managed by  Workpackages 5 and 6.

>> At the biotechnical level (WP1 and WP4) tools will be tested by combining 3 strategies:

  • the lowering of the host parasite probability encounter,  through cattle management
  • favor resilience and resistance of the animal (i.e its ability to sustain the infestation impact)
  • use nutraceuticals or favor a selective treatment of the weakest animals as a way towards the "vertuous use of synthetic drugs".

 >> At the breeding system level (WP5) interactions between biotechnical tools will be measured and integrated to an epidemiologic pattern (WP5). A tool dedicated to decision making will be made to ease knowledge transfer in 2 host/parasite models in tropical and temperate environments. This tool will help breeders make their own integrated control while taking into consideration their prime production system and the economical parameter of their breeding systems.

 >> At the society-territory level: the study related to the perception and motivation of the breeder will lead to proposals regarding tools and methods adapted to the needs (WP6).
 It is necessary to understand how the breeder (and to some aspects the veterinarians as well) build the disease concept and set their prevention and treatment methods.

Organisation du projet STReP © STReP
Organisation du projet STReP © STReP

A consortium at the heart of the project

A consortium of 23 INRA scientists collaborates in full interaction to the core project. It gathers 5 scientific INRA divisions (Animal Health, Animal physiology, Animal genetics, Characterization and making of agricultural products, Social Sciences, Agriculture and Feed, Space and Environment.

Research units are also associated  to experimental units: (Tropical experimental facilities on animal) (Experimental Unit for an alternative breeding of monogastric animals)

The proximity of STReP with 2 mixed technological units will ease knowledge dissemination and biotechnical tools towards breeders and the opening of new development services. Scientists part of the associated veterinary schools will provide information to the veterinary practitioners. Then, the final aim of the STReP project is to enlarge the consortium to foreign scientists with shared symposiums and other european projects.

Scientific contact(s):

Find out more

... on the STReP consortium

- Animal Health Division: http://www.sa.inra.fr/

- Animal Physiology Division: http://www.phase.inra.fr/

- Animal Genetics Division: http://www.ga.inra.fr/

- Characterization and Agricultural Products: http://www.cepia.inra.fr/

- Social Sciences, Agriculture, Feed: http://www.sae2.inra.fr/

- Experimental Unit PTEA:  http://www.antilles.inra.fr/Outils-et-Ressources/ue_ptea

- Experimental Unit Patuchev:  http://www.poitou-charentes.inra.fr/Outils-et-Ressources/Dispositifs-experimentaux/Plateforme-Patuchev/

- Experimental Unit EASM : http://www.poitou-charentes.inra.fr/Le-centre-Les-recherches/Unites-du-centre/EASM/